High-intensity interval training induces lactylation of fatty acid synthase to inhibit lipid synthesis

Abstract Background The aim of study was to observe the effect of increased lactate levels during high-intensity interval training (HIIT) on protein lactylation, identify the target protein, and investigate the regulatory effect of lactylation on the function of the protein. Methods C57B/L6 mice wer...

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Bibliographic Details
Main Authors: Xuefei Chen, Wenhua Huang, Jingbo Zhang, Yanjun Li, Zheng Xing, Lanlan Guo, Hongfeng Jiang, Jing Zhang
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-023-01698-9