WIPI proteins: Biological functions and related syndromes

WIPI proteins: Biological functions and related syndromes

WIPI (WD-repeat protein Interacting with PhosphoInositides) are important effectors in autophagy. These proteins bind phosphoinositides and recruit autophagy proteins. In mammals, there are four WIPI proteins: WIPI1, WIPI2, WIPI3 (WDR45B), and WIPI4 (WDR45). These proteins consist of a seven-bladed...

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Bibliographic Details
Main Authors: Mohammed Almannai, Dana Marafi, Ayman W. El-Hattab
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
WIPI
WD repeat domain
autophagy
neurodevelopment
WDR
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.1011918/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.1011918/full

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