Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition

Defining the altered glycoproteomic space of the early secretory pathway by class I mannosidase pharmacological inhibition

N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response. This is usually accomplished by a complex system of mannosidases in which those from class I have an...

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Bibliographic Details
Main Authors: Cristian V. A. Munteanu, Gabriela N. Chirițoiu, Andrei-Jose Petrescu, Ștefana M. Petrescu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
glycoproteomics
glycosylation
protein degradation
mass-spectrometry
core-fucosylation
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.1064868/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.1064868/full

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