Excess of heme induces tissue factor-dependent activation of coagulation in mice
An excess of free heme is present in the blood during many types of hemolytic anemia. This has been linked to organ damage caused by heme-mediated oxidative stress and vascular inflammation. We investigated the mechanism of heme-induced coagulation activation in vivo. Heme caused coagulation activat...
主要な著者: | , , , , , , , , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
Ferrata Storti Foundation
2015-03-01
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シリーズ: | Haematologica |
オンライン・アクセス: | https://haematologica.org/article/view/7301 |