Genome-Wide DNA Alterations in X-Irradiated Human Gingiva Fibroblasts

Genome-Wide DNA Alterations in X-Irradiated Human Gingiva Fibroblasts

While ionizing radiation (IR) is a powerful tool in medical diagnostics, nuclear medicine, and radiology, it also is a serious threat to the integrity of genetic material. Mutagenic effects of IR to the human genome have long been the subject of research, yet still comparatively little is known abou...

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Bibliographic Details
Main Authors: Neetika Nath, Lisa Hagenau, Stefan Weiss, Ana Tzvetkova, Lars R. Jensen, Lars Kaderali, Matthias Port, Harry Scherthan, Andreas W. Kuss
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
radiation doses
repair mechanism
translocation
transition transversion ratio
IR-induced variants
SNVs
Online Access:https://www.mdpi.com/1422-0067/21/16/5778

Internet

https://www.mdpi.com/1422-0067/21/16/5778

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