Computational guided identification of potential leads from Acacia pennata (L.) Willd. as inhibitors for cellular entry and viral replication of SARS-CoV-2

Abstract Background Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) started in 2019 and is still an on-going pandemic. SARS-CoV-2 uses a human protease called furin to aid in cellular entry and its main protease (Mpro) to achieve viral repli...

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Bibliographic Details
Main Authors: James H. Zothantluanga, Neelutpal Gogoi, Anshul Shakya, Dipak Chetia, H. Lalthanzara
Format: Article
Language:English
Published: SpringerOpen 2021-10-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Online Access:https://doi.org/10.1186/s43094-021-00348-7