Genetic evidence for differential functions of figla and nobox in zebrafish ovarian differentiation and folliculogenesis

Abstract FIGLA and NOBOX are important oocyte-specific transcription factors. Both figla-/- and nobox-/- mutants showed all-male phenotype in zebrafish due to increased dominance of the male-promoting pathway. The early diversion towards males in these mutants has precluded analysis of their roles i...

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Bibliographic Details
Main Authors: Kun Wu, Yue Zhai, Mingming Qin, Cheng Zhao, Nana Ai, Jianguo He, Wei Ge
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05551-1