Targeting Longevity Gene <i>SLC13A5</i>: A Novel Approach to Prevent Age-Related Bone Fragility and Osteoporosis
Reduced expression of the plasma membrane citrate transporter <i>SLC13A5</i>, also known as INDY, has been linked to increased longevity and mitigated age-related cardiovascular and metabolic diseases. Citrate, a vital component of the tricarboxylic acid cycle, constitutes 1–5% of bone w...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-12-01
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Series: | Metabolites |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-1989/13/12/1186 |