Construction of a Human Immune Library from Gallbladder Cancer Patients for the Single-Chain Fragment Variable (<i>scFv</i>) Antibody Selection against Claudin 18.2 via Phage Display

Construction of a Human Immune Library from Gallbladder Cancer Patients for the Single-Chain Fragment Variable (<i>scFv</i>) Antibody Selection against Claudin 18.2 via Phage Display

Gallbladder cancer (GBC) is a very aggressive malignant neoplasm of the biliary tract with a poor prognosis. There are no specific therapies for the treatment of GBC or early diagnosis tools; for this reason, the development of strategies and technologies that facilitate or allow an early diagnosis...

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Bibliographic Details
Main Authors: Brian Effer, Daniel Ulloa, Camila Dappolonnio, Francisca Muñoz, Isabel Iturrieta-González, Loraine Cotes, Claudio Rojas, Pamela Leal
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Antibodies
Subjects:
immune library
phage display
monoclonal antibody
gallbladder cancer
claudin 18.2
Online Access:https://www.mdpi.com/2073-4468/13/1/20

Internet

https://www.mdpi.com/2073-4468/13/1/20

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