Increased Circulating H3 Histone in Response to Repeated Bouts of Exercise Does Not Associate with Parallel Alterations of Cell-Free DNA

Increased Circulating H3 Histone in Response to Repeated Bouts of Exercise Does Not Associate with Parallel Alterations of Cell-Free DNA

Numerous studies have shown that cf nDNA significantly rises in stress caused by exercise. However, during nuclear decondensation, released DNA is followed by histones. Histones are also a common disease marker. After PAD4 mediated hypercitrullination extracellular H3Cit exhibits high toxicity contr...

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Bibliographic Details
Main Authors: Robert Stawski, Konrad Walczak, Ewelina Perdas, Anna Prymont-Przymińska, Anna Zwolińska, Piotr Kosielski, Tomasz Budlewski, Gianluca Padula, Hanna Jerczynska, Dariusz Nowak
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biology
Subjects:
exercise
histone h3
cell-free DNA
aggregation
interleukins
PAD4
Online Access:https://www.mdpi.com/2079-7737/10/3/181

Internet

https://www.mdpi.com/2079-7737/10/3/181

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