c-CSN: Single-cell RNA Sequencing Data Analysis by Conditional Cell-specific Network

c-CSN: Single-cell RNA Sequencing Data Analysis by Conditional Cell-specific Network

The rapid advancement of single-cell technologies has shed new light on the complex mechanisms of cellular heterogeneity. However, compared to bulk RNA sequencing (RNA-seq), single-cell RNA-seq (scRNA-seq) suffers from higher noise and lower coverage, which brings new computational difficulties. Bas...

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Bibliographic Details
Main Authors: Lin Li, Hao Dai, Zhaoyuan Fang, Luonan Chen
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Network flow entropy
Cell-specific network
Single-cell network
Direct association
Conditional independence
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022921000589

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http://www.sciencedirect.com/science/article/pii/S1672022921000589

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