Synthesis, X-ray crystallography and antimicrobial activity of 2-cyanoguanidinophenytoin

Abstract The optimized synthesis of [5-oxo-4,4-diphenylimidazolidin-2-ylidene]cyanamide, which is known as 2-cyanoguanidinophenytoin (CNG-DPH) (3), and (imidazo[4,5-d]imidazole-2,5-diylidine)dicyanamide (4) has been reported in the present work. Furthermore, new Mannich bases derived from CNG-DPH we...

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Bibliographic Details
Main Authors: Ahmed F. Mabied, Amr H. Moustafa, Antar A. Abdelhamid, Taha M. Tiama, Amer A. Amer
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-45533-1