Mycobacterium tuberculosis phosphoribosylpyrophosphate synthetase: biochemical features of a crucial enzyme for mycobacterial cell wall biosynthesis.

Mycobacterium tuberculosis phosphoribosylpyrophosphate synthetase: biochemical features of a crucial enzyme for mycobacterial cell wall biosynthesis.

The selection and soaring spread of Mycobacterium tuberculosis multidrug-resistant (MDR-TB) and extensively drug-resistant strains (XDR-TB) is a severe public health problem. Currently, there is an urgent need for new drugs for tuberculosis treatment, with novel mechanisms of action and, moreover, t...

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Bibliographic Details
Main Authors: Anna P Lucarelli, Silvia Buroni, Maria R Pasca, Menico Rizzi, Andrea Cavagnino, Giovanna Valentini, Giovanna Riccardi, Laurent R Chiarelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21085589/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21085589/?tool=EBI

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