Piceatannol-3′-O-β-D-glucopyranoside attenuates colistin-induced neurotoxicity by suppressing oxidative stress via the NRF2/HO-1 pathway

Piceatannol-3′-O-β-D-glucopyranoside attenuates colistin-induced neurotoxicity by suppressing oxidative stress via the NRF2/HO-1 pathway

Background: Multidrug-resistant Gram-negative bacteria are the most pressing problem in treating infectious diseases. As one of the primary drugs for multidrug-resistant Gram-negative bacteria, the neurotoxicity of colistin has become a significant challenge in clinical practice. Purpose: This study...

Full description

Bibliographic Details
Main Authors: Liguang Xiong, Debiao Xiang, Fang Yuan, Huan Tong, Rui Yang, Lili Zhou, Bing Xu, Changhui Deng, Xin Li
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Colistin
Neurotoxicity
Piceatannol-3′-O-β-D-glucopyranoside (PG)
Apoptosis
NRF2
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222300207X

Internet

http://www.sciencedirect.com/science/article/pii/S075333222300207X

Similar Items