Robust and Repeatable Biofabrication of Bacteria‐Mediated Drug Delivery Systems: Effect of Conjugation Chemistry, Assembly Process Parameters, and Nanoparticle Size

Robust and Repeatable Biofabrication of Bacteria‐Mediated Drug Delivery Systems: Effect of Conjugation Chemistry, Assembly Process Parameters, and Nanoparticle Size

Bacteria‐mediated drug delivery systems comprising nanotherapeutics conjugated onto bacteria synergistically augment the efficacy of both therapeutic modalities in cancer therapy. Nanocarriers preserve therapeutics’ bioavailability and reduce systemic toxicity, while bacteria selectively colonize th...

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Bibliographic Details
Main Authors: Ying Zhan, Austin Fergusson, Lacey R. McNally, Richey M. Davis, Bahareh Behkam
Format: Article
Language:English
Published: Wiley 2022-03-01
Series:Advanced Intelligent Systems
Subjects:
bacteria-based cancer therapy
biohybrid robots
cell-mediated drug delivery systems
Salmonella enterica serovar Typhimurium
tumor-targeting bacteria
Online Access:https://doi.org/10.1002/aisy.202100135

Internet

https://doi.org/10.1002/aisy.202100135

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