Filarial DAF-12 sense the host serum to resume iL3 development during infection.

Filarial DAF-12 sense the host serum to resume iL3 development during infection.

Nematode parasites enter their definitive host at the developmentally arrested infectious larval stage (iL3), and the ligand-dependent nuclear receptor DAF-12 contributes to trigger their development to adulthood. Here, we characterized DAF-12 from the filarial nematodes Brugia malayi and Dirofilari...

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Bibliographic Details
Main Authors: Rémy Bétous, Anthony Emile, Hua Che, Eva Guchen, Didier Concordet, Thavy Long, Sandra Noack, Paul M Selzer, Roger Prichard, Anne Lespine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011462

Internet

https://doi.org/10.1371/journal.ppat.1011462

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