Soluble NKG2DLs Are Elevated in Breast Cancer Patients and Associate with Disease Outcome

Soluble NKG2DLs Are Elevated in Breast Cancer Patients and Associate with Disease Outcome

Ligands of the natural killer group 2D (NKG2DL) family are expressed on malignant cells and are usually absent from healthy tissues. Recognition of NKG2DLs such as MICA/B and ULBP1-3 by the activating immunoreceptor NKG2D, expressed by NK and cytotoxic T cells, stimulates anti-tumor immunity in brea...

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Bibliographic Details
Main Authors: Anna Seller, Christian M. Tegeler, Jonas Mauermann, Tatjana Schreiber, Ilona Hagelstein, Kai Liebel, André Koch, Jonas S. Heitmann, Sarah M. Greiner, Clara Hayn, Dominik Dannehl, Tobias Engler, Andreas D. Hartkopf, Markus Hahn, Sara Y. Brucker, Helmut R. Salih, Melanie Märklin
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:International Journal of Molecular Sciences
Subjects:
NKG2DL
serum marker
breast cancer
DCIS
survival
MIC
Online Access:https://www.mdpi.com/1422-0067/25/7/4126

Internet

https://www.mdpi.com/1422-0067/25/7/4126

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