Glycosphingolipid GM3 prevents albuminuria and podocytopathy induced by anti-nephrin antibody

Abstract Podocytopathy, which is characterized by injury to podocytes, frequently causes proteinuria or nephrotic syndrome. There is currently a paucity of effective therapeutic drugs to treat proteinuric kidney disease. Recent research suggests the possibility that glycosphingolipid GM3 maintains p...

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Bibliographic Details
Main Authors: Nagako Kawashima, Shokichi Naito, Hisatoshi Hanamatsu, Masaki Nagane, Yasuo Takeuchi, Jun-ichi Furukawa, Norimasa Iwasaki, Tadashi Yamashita, Ken-ichi Nakayama
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20265-w