Cholangiocarcinoma Malignant Traits Are Promoted by Schwann Cells through TGFβ Signaling in a Model of Perineural Invasion

Cholangiocarcinoma Malignant Traits Are Promoted by Schwann Cells through TGFβ Signaling in a Model of Perineural Invasion

The term cholangiocarcinoma (CCA) defines a class of epithelial malignancies originating from bile ducts. Although it has been demonstrated that CCA patients with perineural invasion (PNI) have a worse prognosis, the biological features of this phenomenon are yet unclear. Our data show that in human...

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Bibliographic Details
Main Authors: Valerio de Franchis, Simonetta Petrungaro, Elisa Pizzichini, Serena Camerini, Marialuisa Casella, Francesca Somma, Enrico Mandolini, Guido Carpino, Diletta Overi, Vincenzo Cardinale, Antonio Facchiano, Antonio Filippini, Eugenio Gaudio, Cinzia Fabrizi, Claudia Giampietri
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cells
Subjects:
bile duct cancer
Schwann cells
TGFβ
EMT
Online Access:https://www.mdpi.com/2073-4409/13/5/366

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https://www.mdpi.com/2073-4409/13/5/366

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