Genome-Wide Placental Gene Methylations in Gestational Diabetes Mellitus, Fetal Growth and Metabolic Health Biomarkers in Cord Blood

Genome-Wide Placental Gene Methylations in Gestational Diabetes Mellitus, Fetal Growth and Metabolic Health Biomarkers in Cord Blood

Gestational diabetes mellitus (GDM) “program” an elevated risk of metabolic syndrome in the offspring. Epigenetic alterations are a suspected mechanism. GDM has been associated with placental DNA methylation changes in some epigenome-wide association studies. It remains unclear which genes or pathwa...

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Bibliographic Details
Main Authors: Wen-Juan Wang, Rong Huang, Tao Zheng, Qinwen Du, Meng-Nan Yang, Ya-Jie Xu, Xin Liu, Min-Yi Tao, Hua He, Fang Fang, Fei Li, Jian-Gao Fan, Jun Zhang, Laurent Briollais, Fengxiu Ouyang, Zhong-Cheng Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Endocrinology
Subjects:
GDM
fetal growth
placental DNA methylations
cord blood biomarkers
birth weight
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.875180/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.875180/full

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