The Genetic Stability, Replication Kinetics and Cytopathogenicity of Recombinant Avian Coronaviruses with a T16A or an A26F Mutation within the E Protein Is Cell-Type Dependent

The Genetic Stability, Replication Kinetics and Cytopathogenicity of Recombinant Avian Coronaviruses with a T16A or an A26F Mutation within the E Protein Is Cell-Type Dependent

The envelope (E) protein of the avian coronavirus infectious bronchitis virus (IBV) is a small-membrane protein present in two forms during infection: a monomer and a pentameric ion channel. Each form has an independent role during replication; the monomer disrupts the secretory pathway, and the pen...

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Bibliographic Details
Main Authors: Isobel Webb, Sarah Keep, Kieran Littolff, Jamie Stuart, Graham Freimanis, Paul Britton, Andrew D. Davidson, Helena J. Maier, Erica Bickerton
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Viruses
Subjects:
avian coronavirus
cell type
envelope protein
chicken
viroporin
Online Access:https://www.mdpi.com/1999-4915/14/8/1784

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https://www.mdpi.com/1999-4915/14/8/1784

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