Cell Immortalization: In Vivo Molecular Bases and In Vitro Techniques for Obtention

Cell Immortalization: In Vivo Molecular Bases and In Vitro Techniques for Obtention

Somatic human cells can divide a finite number of times, a phenomenon known as the Hayflick limit. It is based on the progressive erosion of the telomeric ends each time the cell completes a replicative cycle. Given this problem, researchers need cell lines that do not enter the senescence phase aft...

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Bibliographic Details
Main Authors: Javier Curi de Bardet, Celeste Ramírez Cardentey, Belkis López González, Deanira Patrone, Idania Lores Mulet, Dario Siniscalco, María de los Angeles Robinson-Agramonte
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:BioTech
Subjects:
Hayflick limit
telomeres
telomerase
alternative telomere elongation
immortalization
Online Access:https://www.mdpi.com/2673-6284/12/1/14

Internet

https://www.mdpi.com/2673-6284/12/1/14

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