Genome length determination in adeno-associated virus vectors with mass photometry

Genome length determination in adeno-associated virus vectors with mass photometry

Recombinant adeno-associated viruses (rAAVs) are attractive therapeutic viral vectors for gene delivery. To ensure the efficacy and safety of rAAV-based therapies, comprehensive characterization of the adeno-associated virus (AAV) capsids is essential. Mass photometry (MP) provides the advantage of...

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Bibliographic Details
Main Authors: Cornelia Hiemenz, Nadine Baumeister, Constanze Helbig, Andrea Hawe, Sabrina Babutzka, Stylianos Michalakis, Wolfgang Friess, Tim Menzen
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
gene therapy
recombinant adeno-associated virus
rAAV
mass photometry
MP
genome length
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050123002012

Internet

http://www.sciencedirect.com/science/article/pii/S2329050123002012

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