Cerebral White Matter Hyperintensities, Kidney Function Decline, and Recurrent Stroke After Intensive Blood Pressure Lowering: Results From the Secondary Prevention of Small Subcortical Strokes (SPS3) Trial

Cerebral White Matter Hyperintensities, Kidney Function Decline, and Recurrent Stroke After Intensive Blood Pressure Lowering: Results From the Secondary Prevention of Small Subcortical Strokes (SPS3) Trial

Background We aimed to determine whether cerebral white matter hyperintensities (WMHs) can distinguish stroke survivors susceptible to rapid kidney function decline from intensive blood pressure (BP) lowering. Methods and Results The SPS3 (Secondary Prevention of Small Subcortical Strokes) trial ran...

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Bibliographic Details
Main Authors: Jesse C. Ikeme, Pablo E. Pergola, Rebecca Scherzer, Michael G. Shlipak, Luciana Catanese, Leslie A. McClure, Oscar R. Benavente, Carmen A. Peralta
Format: Article
Language:English
Published: Wiley 2019-02-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
blood pressure
creatinine
estimated glomerular filtration rate
kidney
lacunar stroke
secondary prevention of small subcortical strokes
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.010091

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.118.010091

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