Kinetic contribution to extracellular Na+/K+ selectivity in the Na+/K+ pump

The sodium potassium pump (Na+,K+‐ATPase) shows a high selectivity for K+ over Na+ binding from the extracellular medium. To understand the K+ selectivity in the presence of a high concentration of competing Na+ ions requires consideration of more than just ion binding affinities. Here, equilibrium‐...

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Bibliographic Details
Main Authors: Elizabeth Vleeskens, Ronald J. Clarke
Format: Article
Language:English
Published: Wiley 2018-05-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12418