Apolipoprotein E genotyping using the polymerase chain reaction and allele-specific oligonucleotide primers.
A method for apolipoprotein (apo) E genotyping was developed using the polymerase chain reaction (PCR) with allele-specific oligonucleotide primers (ASP). Synthetic oligonucleotides with base-pair mismatches at the 3' terminus were used as primers to amplify the apoE gene in subjects previously...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1991-01-01
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Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520422576 |