The Cumulative Formation of R-loop Interacts with Histone Modifications to Shape Cell Reprogramming

R-loop, a three-stranded RNA/DNA structure, plays important roles in modulating genome stability and gene expression, but the molecular mechanism of R-loops in cell reprogramming remains elusive. Here, we comprehensively profiled the genome-wide landscape of R-loops during cell reprogramming. The re...

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Bibliographic Details
Main Authors: Hanshuang Li, Chunshen Long, Yan Hong, Lemuge Chao, Yong Peng, Yongchun Zuo
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/3/1567