Cytokine and reactivity profiles in SLE patients following anti-CD19 CART therapy

Cytokine and reactivity profiles in SLE patients following anti-CD19 CART therapy

Chimeric antigen receptor (CAR) T cells targeting CD19+ B cells have demonstrated efficacy in refractory systemic lupus erythematosus (SLE). Although initial clinical data suggest that anti-CD19 CAR T cell therapy is well tolerated and highly effective, the immunologic consequences of CAR T cell the...

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Bibliographic Details
Main Authors: Daniel Nunez, Darshil Patel, Jenell Volkov, Steven Wong, Zachary Vorndran, Fabian Müller, Michael Aigner, Simon Völkl, Andreas Mackensen, Georg Schett, Samik Basu
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
chimeric antigen receptor T cell
CAR
systemic lupus erythematous
SLE
cytokines
antibodies
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050123001377

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http://www.sciencedirect.com/science/article/pii/S2329050123001377

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