Tautomerism troubles: proton transfer modifies the stereochemical assignments in diastereoisomeric structures of spirocyclic 5-methyl-2H-imidazol-4-amine dimers

Tautomerism troubles: proton transfer modifies the stereochemical assignments in diastereoisomeric structures of spirocyclic 5-methyl-2H-imidazol-4-amine dimers

During the racemization of a novel pharmaceutical spirocyclic imidazole–amine compound, namely, 6′-bromo-N-(6′-bromo-4-methoxy-4′′-methyl-3′H-dispiro[cyclohexane-1,2′-indene-1′,2′′-imidazol]-5′′-yl)-4-methoxy-4′′-methyl-3′H-dispiro[cyclohexane-1,2′-indene-1′,2′′-imidazol]-5′′-imine, C36H41Br2N5O2, t...

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Bibliographic Details
Main Authors: Helen Blade, Peter N. Horton, James A. Morrison, James B. Orton, Rachel A. Sullivan, Simon J. Coles
Format: Article
Language:English
Published: International Union of Crystallography 2021-12-01
Series:Acta Crystallographica Section E: Crystallographic Communications
Subjects:
chirality assignment
pharmaceutical
crystal structure
Online Access:http://scripts.iucr.org/cgi-bin/paper?S205698902100668X

Internet

http://scripts.iucr.org/cgi-bin/paper?S205698902100668X

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