Longitudinal hair cortisol in bipolar disorder and a mechanism based on HPA dynamics

Summary: Bipolar disorder (BD) is marked by fluctuating mood states over months to years, often with elevated cortisol levels. Elevated cortisol can also trigger mood episodes. Here, we combine longitudinal hair cortisol and mood measurements with mathematical modeling to provide a potential mechani...

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Bibliographic Details
Main Authors: Tomer Milo, Lior Maimon, Ben Cohen, Dafna Haran, Dror Segman, Tamar Danon, Anat Bren, Avi Mayo, Gadi Cohen Rappaport, Melvin McInnis, Uri Alon
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224004553