Hydroxytyrosol inhibits MAO isoforms and prevents neurotoxicity inducible by MPP+ in vivo

Parkinson’s disease is considered to be due to an increase in the catabolism of dopamine by the action of monoamine oxidase (MAO) enzymes which leads to an increase in reactive oxygen species (ROS) and loss of dopaminergic neurons. Here, in a model of neurotoxicity inducible by 1-methyl-4-phenylpyri...

Full description

Bibliographic Details
Main Authors: Gabriela A. Perez-Barron, Sergio Montes, Moises Rubio-Osornio, Jose G. Avila-Acevedo, Sara Garcia-Jimenez, Luis C. Rios, Antonio Monroy-Noyola
Format: Article
Language:English
Published: IMR Press 2020-01-01
Series:Frontiers in Bioscience-Scholar
Subjects:
Online Access:https://www.imrpress.com/journal/FBS/12/1/10.2741/S538