Development of a novel tocopheryl ester for suppression of lipid accumulation without cytotoxicity by optimization of dicarboxylic ester moiety

Tocopheryl succinate (Tsuc) is a succinic acid ester of the well-known antioxidant α-tocopherol (T). Tsuc exhibits various biological activities, including tumor growth suppression via activation of cell signaling and prevention of lipid accumulation in mouse adipocyte 3T3-L1 cells. The latter findi...

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Bibliographic Details
Main Authors: Misaki Yamasaki, Yuika Seto, Mizune Ozono, Michiyasu Nakao, Akira Shigenaga, Akira Otaka, Shigeki Sano, Kentaro Kogure
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580822001297