Azurophil granule proteins constitute the major mycobactericidal proteins in human neutrophils and enhance the killing of mycobacteria in macrophages.

Azurophil granule proteins constitute the major mycobactericidal proteins in human neutrophils and enhance the killing of mycobacteria in macrophages.

Pathogenic mycobacteria reside in, and are in turn controlled by, macrophages. However, emerging data suggest that neutrophils also play a critical role in innate immunity to tuberculosis, presumably by their different antibacterial granule proteins. In this study, we purified neutrophil azurophil a...

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Bibliographic Details
Main Authors: Prajna Jena, Soumitra Mohanty, Tirthankar Mohanty, Stephanie Kallert, Matthias Morgelin, Thomas Lindstrøm, Niels Borregaard, Steffen Stenger, Avinash Sonawane, Ole E Sørensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3522671?pdf=render

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http://europepmc.org/articles/PMC3522671?pdf=render

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