Efficacy of propofol-supplemented cardioplegia on biomarkers of organ injury in patients having cardiac surgery using cardiopulmonary bypass: a statistical analysis plan for the ProMPT-2 randomised controlled trial

Efficacy of propofol-supplemented cardioplegia on biomarkers of organ injury in patients having cardiac surgery using cardiopulmonary bypass: a statistical analysis plan for the ProMPT-2 randomised controlled trial

Abstract Background The ProMPT-2 trial (Propofol for Myocardial Protection Trial #2) aims to compare the safety and efficacy of low- and high-dose propofol supplementation of the cardioplegia solution during adult cardiac surgery versus sham supplementation. This update presents the statistical anal...

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Bibliographic Details
Main Authors: Helena Smartt, Gianni D. Angelini, Ben Gibbison, Chris A. Rogers
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Trials
Subjects:
Cardiac surgery
Cardiopulmonary bypass
Cardioplegia
Ischaemia
Reperfusion
Propofol
Online Access:https://doi.org/10.1186/s13063-024-08016-w

Internet

https://doi.org/10.1186/s13063-024-08016-w

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