Promising preclinical patient-derived organoid (PDO) and xenograft (PDX) models in upper gastrointestinal cancers: progress and challenges

Promising preclinical patient-derived organoid (PDO) and xenograft (PDX) models in upper gastrointestinal cancers: progress and challenges

Abstract Gastrointestinal (GI) cancers (gastric cancer, oesophageal cancer, liver cancer, colorectal cancer, etc.) are the most common cancers with the highest morbidity and mortality in the world. The therapy for most GI cancers is difficult and is associated with a poor prognosis. In China, upper...

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Bibliographic Details
Main Authors: Jing Gao, Jianqiang Lan, Haiyan Liao, Fang Yang, Pei Qiu, Feng Jin, Shubin Wang, Lin Shen, Tengfei Chao, Cheng Zhang, Yu Zhu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Cancer
Subjects:
Upper gastrointestinal cancer
Organoid
PDX
Personalized therapy
Online Access:https://doi.org/10.1186/s12885-023-11434-9

Internet

https://doi.org/10.1186/s12885-023-11434-9

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