Reproducibility in pharmacometrics applied in a phase III trial of BCG-vaccination for COVID-19

Abstract Large clinical trials often generate complex and large datasets which need to be presented frequently throughout the trial for interim analysis or to inform a data safety monitory board (DSMB). In addition, reliable and traceability are required to ensure reproducibility in pharmacometric d...

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Bibliographic Details
Main Authors: Rob C. van Wijk, Laurynas Mockeliunas, Gerben van den Hoogen, Caryn M. Upton, Andreas H. Diacon, Ulrika S. H. Simonsson
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43412-3