Regional glucose hypometabolic spread within the primary motor cortex is associated with amyotrophic lateral sclerosis disease progression: A fluoro-deoxyglucose positron emission tomography study

Objective: Here we investigate the process of neurodegeneration in amyotrophic lateral sclerosis (ALS). The relationship between the cortical field spreading of glucose metabolic decreases in the primary motor cortex (PMC) and the progression of corresponding extremity dysfunction was evaluated usin...

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Bibliographic Details
Main Authors: Hironobu Endo, Kenji Sekiguchi, Takehiro Ueda, Hisatomo Kowa, Fumio Kanda, Tatsushi Toda
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:eNeurologicalSci
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405650217300011