Targeting ferroptosis suppresses osteocyte glucolipotoxicity and alleviates diabetic osteoporosis

Targeting ferroptosis suppresses osteocyte glucolipotoxicity and alleviates diabetic osteoporosis

Abstract Diabetic osteoporosis (DOP) is the leading complication continuously threatening the bone health of patients with diabetes. A key pathogenic factor in DOP is loss of osteocyte viability. However, the mechanism of osteocyte death remains unclear. Here, we identified ferroptosis, which is iro...

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Bibliographic Details
Main Authors: Yiqi Yang, Yixuan Lin, Minqi Wang, Kai Yuan, Qishan Wang, Pei Mu, Jingke Du, Zhifeng Yu, Shengbing Yang, Kai Huang, Yugang Wang, Hanjun Li, Tingting Tang
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-022-00198-w

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https://doi.org/10.1038/s41413-022-00198-w

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