The methylenetetrahydrofolate reductase genotype 677CT and non-alcoholic fatty liver disease have a synergistic effect on the increasing homocysteine levels in subjects from Chongqing, China

The methylenetetrahydrofolate reductase (MTHFR) genotypes 677CT and 677TT are associated with elevated serum homocysteine (Hcy) levels by means of lowering the activity of MTHFR, and the increase in serum Hcy may be linked to increased susceptibility to non-alcoholic fatty liver disease (NAFLD). How...

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Bibliographic Details
Main Authors: Xiaolin Wang, Yongli Zhou, Mingjun Zhang, Yonghong Wang, Bo Qin
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-03-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304218300175