Antagonistic Roles of the Tumor Suppressor miR-210-3p and Oncomucin MUC4 Forming a Negative Feedback Loop in Pancreatic Adenocarcinoma

Antagonistic Roles of the Tumor Suppressor miR-210-3p and Oncomucin MUC4 Forming a Negative Feedback Loop in Pancreatic Adenocarcinoma

Background: Pancreatic adenocarcinoma (PDAC) is a deadly cancer with an extremely poor prognosis. MUC4 membrane-bound mucin is neoexpressed in early pancreatic neoplastic lesions and is associated with PDAC progression and chemoresistance. In cancers, microRNAs (miRNAs, small noncoding RNAs) are cru...

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Bibliographic Details
Main Authors: Nihad Boukrout, Mouloud Souidi, Fatima Lahdaoui, Belinda Duchêne, Bernadette Neve, Lucie Coppin, Emmanuelle Leteurtre, Jérôme Torrisani, Isabelle Van Seuningen, Nicolas Jonckheere
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
pancreatic cancer
MUC4
miR-210-3p
anti-tumoral miR
Online Access:https://www.mdpi.com/2072-6694/13/24/6197

Internet

https://www.mdpi.com/2072-6694/13/24/6197

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