Nasal Administration of Lipopolysaccharide Exacerbates Allergic Rhinitis through Th2 Cytokine Production from Mast Cells

Background: Microbial infection or exposure to endotoxin later in life exacerbates established asthma. Mast cells are involved in the exacerbation of asthma. This exacerbation involves a toll-like receptor (TLR)–mediated response of mast cells. In the clinical practice of otolaryngology, otolaryngol...

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Bibliographic Details
Main Authors: Noriaki Aoi, Takafumi Fuchiwaki, Ichiro Morikura, Hideyuki Kawauchi, Tatsunori Sakamoto
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Allergies
Subjects:
Online Access:https://www.mdpi.com/2313-5786/1/4/20