Effects of oral losartan administration on homeostasis of articular cartilage and bone in a rabbit model

Background and aims: Previous work has shown that oral losartan can enhance microfracture-mediated cartilage repair in a rabbit osteochondral defect injury model. In this study, we aimed to determine whether oral losartan would have a detrimental effect on articular cartilage and bone homeostasis in...

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Bibliographic Details
Main Authors: Zhenhan Deng, Xueqin Gao, Hajime Utsunomiya, Justin W. Arner, Joseph J. Ruzbarsky, Matthieu Huard, Sudheer Ravuri, Marc J. Philippon, Johnny Huard
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Bone Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187222003606