In vivo islet protection by a nuclear import inhibitor in a mouse model of type 1 diabetes.

Insulin-dependent Type 1 diabetes (T1D) is a devastating autoimmune disease that destroys beta cells within the pancreatic islets and afflicts over 10 million people worldwide. These patients face life-long risks for blindness, cardiovascular and renal diseases, and complications of insulin treatmen...

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Bibliographic Details
Main Authors: Daniel J Moore, Jozef Zienkiewicz, Peggy L Kendall, Danya Liu, Xueyan Liu, Ruth Ann Veach, Robert D Collins, Jacek Hawiger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2950856?pdf=render