Synthesis, antileishmanial, antimalarial evaluation and molecular docking study of some hydrazine-coupled pyrazole derivatives

Synthesis, antileishmanial, antimalarial evaluation and molecular docking study of some hydrazine-coupled pyrazole derivatives

Abstract Pyrazole-bearing compounds are known for their diverse pharmacological effects including potent antileishmanial and antimalarial activities. Herein, some hydrazine-coupled pyrazoles were successfully synthesized and their structures were verified by employing elemental microanalysis, FTIR,...

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Bibliographic Details
Main Authors: Halefom Gebreselasse Berhe, Yihenew Simegniew Birhan, Botros Youssef Beshay, Huda Jawad Habib, Ariaya Hymete, Adnan Ahmed Bekhit
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Chemistry
Subjects:
Hydrazine-coupled pyrazoles
Antileishmanial activities
Antimalarial activities
Molecular docking
Online Access:https://doi.org/10.1186/s13065-023-01111-0

Internet

https://doi.org/10.1186/s13065-023-01111-0

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