The Impact of Innate Components on Viral Pathogenesis in the Neurotropic Coronavirus Encephalomyelitis Mouse Model

The Impact of Innate Components on Viral Pathogenesis in the Neurotropic Coronavirus Encephalomyelitis Mouse Model

Recognition of viruses invading the central nervous system (CNS) by pattern recognition receptors (PRRs) is crucial to elicit early innate responses that stem dissemination. These innate responses comprise both type I interferon (IFN-I)-mediated defenses as well as signals recruiting leukocytes to c...

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Bibliographic Details
Main Authors: Brendan T. Boylan, Mihyun Hwang, Cornelia C. Bergmann
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Viruses
Subjects:
murine hepatitis virus
neurotropic coronavirus
encephalomyelitis
interferons
interferon stimulated genes
pattern recognition receptors
Online Access:https://www.mdpi.com/1999-4915/15/12/2400

Internet

https://www.mdpi.com/1999-4915/15/12/2400

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