Single-Cell Analysis Reveals Transcriptomic Reprogramming in Aging Cardiovascular Endothelial Cells

Single-Cell Analysis Reveals Transcriptomic Reprogramming in Aging Cardiovascular Endothelial Cells

The senescence of cardiovascular endothelial cells (ECs) is a major risk factor in the development of aging-related cardiovascular diseases. However, the molecular dynamics in cardiovascular EC aging are poorly understood. Here, we characterized the transcriptomic landscape of cardiovascular ECs dur...

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Bibliographic Details
Main Authors: Bo Gou, Xiaojing Chu, Yi Xiao, Pinxuan Liu, Hao Zhang, Zeyu Gao, Moshi Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
senescence
cardiovascular endothelial cells
scRNA-seq
age-dependent genes
transcriptomic reprogramming
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.900978/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.900978/full

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