Revitalizing the AZT Through of the Selenium: An Approach in Human Triple Negative Breast Cancer Cell Line

Revitalizing the AZT Through of the Selenium: An Approach in Human Triple Negative Breast Cancer Cell Line

Triple-negative breast cancer represents about 15% of all cases of breast cancer, and still represents a therapeutic challenge. 3′-Azido-3′-deoxythymidine (AZT) is a nucleoside reverse transcriptase inhibitor with antitumor activity. Chalcogenides compounds, such as selenium, are very important inte...

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Bibliographic Details
Main Authors: Mônica Silveira Wagner, Eduarda Schultze, Thais Larre Oliveira, Priscila Marques Moura de Leon, Helena Strelow Thurow, Vinicius Farias Campos, Isabel Oliveira, Diego de Souza, Oscar Endrigo Dorneles Rodrigues, Tiago Collares, Fabiana Kömmling Seixas
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Oncology
Subjects:
AZT
selenium
breast cancer
triple negative
apoptosis induction
anticancer agents
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00525/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2018.00525/full

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