Loss of Sarm1 reduces retinal ganglion cell loss in chronic glaucoma

Abstract Glaucoma is one of the leading causes of irreversible blindness worldwide and vision loss in the disease results from the deterioration of retinal ganglion cells (RGC) and their axons. Metabolic dysfunction of RGC plays a significant role in the onset and progression of the disease in both...

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Bibliographic Details
Main Authors: Huilan Zeng, Jordan E. Mayberry, David Wadkins, Nathan Chen, Daniel W. Summers, Markus H. Kuehn
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Acta Neuropathologica Communications
Subjects:
Online Access:https://doi.org/10.1186/s40478-024-01736-9