Optical inhibition of larval zebrafish behaviour with anion channelrhodopsins

Abstract Background Optical silencing of activity provides a way to test the necessity of neurons in behaviour. Two light-gated anion channels, GtACR1 and GtACR2, have recently been shown to potently inhibit activity in cultured mammalian neurons and in Drosophila. Here, we test the usefulness of th...

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Bibliographic Details
Main Authors: Gadisti Aisha Mohamed, Ruey-Kuang Cheng, Joses Ho, Seetha Krishnan, Farhan Mohammad, Adam Claridge-Chang, Suresh Jesuthasan
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12915-017-0430-2