Ruled by Ubiquitylation: A New Order for Polycomb Recruitment

Polycomb complexes are found in most cells, but they must be targeted to specific genes in specific cell types in order to regulate pluripotency and differentiation. The recruitment of Polycomb complexes to specific targets has been widely thought to occur in two steps: first, one complex, PRC2, pro...

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Bibliographic Details
Main Authors: Yuri B. Schwartz, Vincenzo Pirrotta
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714005658